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Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
1oqy A
1qze A

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 177 R 181 V 1.13
2 196 E 200 T 0.91
3 164 E 168 T 0.87
4 168 T 172 S 0.87
5 171 M 177 R 0.86
6 173 M 195 V 0.71
7 197 Y 201 G 0.66
8 170 I 195 V 0.66
9 171 M 180 V 0.63
10 175 Y 198 L 0.61
11 184 L 189 N 0.59
12 175 Y 199 L 0.54
13 167 L 180 V 0.54
14 179 R 198 L 0.53
15 162 E 189 N 0.51
16 164 E 177 R 0.50
17 109 S 115 P 0.48
18 119 R 123 S 0.47
19 195 V 199 L 0.47
20 184 L 194 A 0.46
21 102 S 110 G 0.46
22 165 T 169 E 0.45
23 113 H 117 A 0.44
24 164 E 181 V 0.44
25 137 V 141 V 0.43
26 166 M 184 L 0.43
27 146 S 150 E 0.43
28 169 E 191 P 0.42
29 162 E 167 L 0.42
30 147 S 151 E 0.41
31 182 A 197 Y 0.41
32 163 Y 189 N 0.41
33 184 L 190 N 0.40

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness